Overview
GHK-Cu is a naturally occurring tripeptide (glycyl-histidyl-lysine) that forms a complex with copper ions. Found abundantly in young plasma and declining sharply with age, it is studied for its potent regenerative, anti-inflammatory, and gene-modulating effects.
Mechanism of action
GHK-Cu modulates expression of over 4,000 human genes, generally resetting them toward a more youthful pattern. It stimulates collagen and elastin synthesis, activates antioxidant defenses, attracts immune cells to wounds, and supports hair-follicle stem cells.
Reported benefits
- Stimulates collagen, elastin, and glycosaminoglycan production
- Improves skin firmness, elasticity, and wound healing
- Reduces appearance of fine lines and hyperpigmentation
- Promotes hair growth and follicle health
- Strong antioxidant and anti-inflammatory action
Research dosing
Subcutaneous research protocols: 1–2 mg daily or every other day. Topical applications are also common for skin and hair-focused studies.
Considerations
Often used in regeneration stacks (e.g., GLOW, KLOW). The copper component is essential — pure GHK without copper is significantly less active.
Research use only. This article is provided for educational purposes and is not medical advice. Products sold on this website are for laboratory research only and are not intended for human consumption. Not evaluated by the FDA.
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